Menopause is a natural process characterized by a reduction in certain gonadal hormones in females in their 40s. A lot of changes can be seen as the symptoms of menopause, such as those related to the central nervous system, metabolic changes, and weight gain, changes in cardiovascular health, urogenital and skin problems, and sexual dysfunction. Transdermal mode of delivery provides a practical and less risky alternative to oral consumption of drugs and also aims to serve as a better alternative to hypodermic injection. Topical Wild yam releases diosgenin, a precursor of gonadal hormone for managing menopausal symptoms and balancing hormones.
A cohort study was done on females of age 40-49 years, who were experiencing menopausal symptoms. The observation of a group of 34 females was done over time of 21 days (three weeks-three follow-ups) on Dr Skin BEAUTY™ Wild Yam Hormonal Salve followed by placebo effect (14 days) to assess the impact of intervention. A purposive non-probability sampling technique was used to collect the data on designed questionnaire, to test the effectiveness of a natural balm, Dr Skin BEAUTY™ Wild Yam Hormonal Salve. An informed consent was taken from every participant before intervention.
Results: Throughout the three subsequent evaluations, there was a persistent pattern of escalating beneficial outcomes observed with extended utilization of the hormonal salve, Dr Skin BEAUTY™ Wild Yam Hormonal Salve. Most individuals did not encounter any adverse effects, which reinforces the salve's safety profile. The occurrence of night sweats showed a consistent improvement, reaching a relief rate of 82.3% after duration of three weeks. At the start, vaginal dryness was a common problem for 85.2% of participants. However, after 21 days, there was a significant improvement, with 73.5% of participants reporting alleviation. The study consistently showed a good trend in both sleep disturbances and mood disturbances, with a sustained improvement of 76.5% recorded at the final follow-up. The decrease in sexual desire elicited diverse reactions, with a significant rise in the number of individuals (47.1%) expressing positive changes after a period of 21 days. Considerable alleviation of symptoms such as hot flashes, and joint/muscle discomfort was seen, underscoring the importance of ongoing monitoring. Significantly, the issue of weight increase, which was a concern for 11.8% of participants at the beginning, showed no change till last follow-up with the salve.
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